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yup...
fair warning - Domino is an I/O abuser and so is TSM, so depending on what each instance is doing it might not be the best idea ever...
yes, been there - use shared memory instead of tcpip for your commmethod Works fine.
Mm its been a little while since they shared a node...would have been a 5.umm...
No reason that I'm aware of that 5.5 would have an issue in any way...I guess there's a vague chance that a DB2 enabled Domino + TSM 6 might have an interop problem...something to check I guess. TSM is quite happy to run multiple DB2 instances on a node...not sure about versioning issues with a Domino DB2 instance though.