Bob,

We've installed the TSM 6.2.2 client on a virtual machine that we designated as 
a backup proxy within vSphere 4.1. We can confirm that 6.2.2 does use the TSM 
API's directly for full image backups (new to 6.2.2) as well as support for 
agentless file-level backups (which shipped in 6.2). Here is a presentation 
from PULSE ANZ that provides an overview, somewhat. 
ftp://ftp.software.ibm.com/software/au/downloads/pulse_ANZ/sm/Session9.pdf

Let me know how your testing goes!

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