This is the exclude list I used for XP and 7, might be worth a try
$Conf{BackupFilesExclude} = {
'*' => [
'/Documents and Settings',
'/ProgramData/Application Data',
'/ProgramData/Desktop',
'/ProgramData/Documents',
'/ProgramData/Favorites',
'/ProgramData/Start Menu',
'/ProgramData/Templates',
'/Users/All Users',
'/Users/Users/Default User',
'/Users/Users/All Users/Application Data',
'/Users/Users/All Users/Desktop',
'/Users/All Users/Documents',
'/Users/All Users/Favorites',
'/Users/All Users/Start Menu',
'/Users/All Users/Templates',
'/Users/*/Application Data',
'/Users/*/Cookies',
'/Users/*/Local Settings',
'/Users/*/My Documents',
'/Users/*/NetHood',
'/Users/*/PrintHood',
'/Users/*/Recent',
'/Users/*/SendTo',
'/Users/*/Start Menu',
'/Users/*/Templates',
'/Users/*/AppData/Local/Application Data',
'/Users/*/AppData/Local/History',
'/Users/*/AppData/Local/Temporary Internet Files',
'/Users/*/Documents/My Music',
'/Users/*/Documents/My Pictures',
'/Users/*/Documents/My Videos',
'/Users/*/AppData/Local/Microsoft/Windows/Temporary Internet Files',
'/Users/*/AppData/Local/Temp',
'/Users/*/NTUSER.DAT*',
'/Users/*/ntuser.dat*',
'/Users/*/AppData/Local/Microsoft/Windows/UsrClass.dat*',
'/Users/*/AppData/Local/Microsoft/Windows Defender/FileTracker',
'/Users/*/AppData/Local/Microsoft/Windows/Explorer/thumbcache_*.db',
'/Users/*/AppData/Local/Microsoft/Windows/WER',
'/Users/*/AppData/Local/Mozilla/Firefox/Profiles/*/Cache',
'/Users/*/AppData/Local/Mozilla/Firefox/Profiles/*/OfflineCache',
'/Users/*/AppData/Roaming/Microsoft/Windows/Cookies',
'/Users/*/AppData/Roaming/Microsoft/Windows/Recent',
'ProgramData/Microsoft/Search',
'ProgramData/Microsoft/Windows Defender',
'*.lock',
'Thumbs.db',
'IconCache.db',
'Cache*',
'cache*',
'/Program Files',
'/Windows',
'/$Recycle.Bin',
'/MSOCache',
'/System Volume Information',
'/Boot',
'/autoexec.bat',
'/bootmgr',
'/BOOTSECT.BAK',
'/config.sys',
'/hiberfil.sys',
'/pagefile.sys',
'/AppData'
]
};