My co-worker Nate found this today:

You can find more details at the link below, but the summary is this: If you've 
expanded an NTFS volume and the $BITMAP part of the MFT becomes fragmented in 
the process, and you take a FlashBackup with  the "Exclude unused and deleted 
blocks" option Enabled in the snapshot options (which we do, at least on the 
VMWARE.adhoc.TEST policy), then it will discard fragments of the $BITMAP, 
thereby trashing the filesystem and, by extension, the backup.

This can be fixed by disabling the option "Exclude unused and deleted blocks" 
in the snapshot options for the policy, but, based on my experience with the 
VMWare server, restores will take about 2.5 times as long.

In the meantime, I'd say we'll certainly want to make sure to disable the 
"Exclude unused and deleted blocks" option on all of our VMware backups ASAP.

Symantec says that this bug is patched in NetBackup for VMware 7.1.0.1.
This issue affects the following versions of NetBackup for VMware:
 *NetBackup 7.1 
 *NetBackup 7.0/7.0.1 when certain Emergency Engineering Binaries have been 
applied

See here for more details: 
http://www.symantec.com/business/support/index?page=content&id=TECH160324

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