Im not a Windows guy by trade but yes it does matter.

It will contain all users application data and things like Office 
personal files etc. oh and not to mention any documents which are stored 
in My Documents.

Start to browse the directory and you will hopefully see the things in 
there.

Cheers

Shyam Hazari wrote:
> Majority of my Windows hosts get Status code 1 and I am looking at the 
> error log, most of them fail to backup files in C:\Documents and 
> Settings\. The question is, does this folder has any useful data that 
> needs recovery or can it be safely excluded ?
>
> TIA
>
> -Shyam
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