Try to put everything in the hosts file.
Networker has always some problem with multiple nics but you can solve this 
with the client configuration and aliases

Kind regards

> Date: Sun, 10 Jan 2010 09:12:51 -0600
> From: anacreo AT GMAIL DOT COM
> Subject: Re: [Networker] Sharepoint Granular backups
> To: NETWORKER AT LISTSERV.TEMPLE DOT EDU
> 
> What is the error you're receiving?  I'm not sure why NetWorker would care
> so much about the 2 NIC setup as long as the data is going out and coming
> back along the same path.
> 
> Alec
> 
> On Thu, Jan 7, 2010 at 1:40 PM, marven000 <networker-forum AT backupcentral 
> DOT com
> > wrote:
> 
> > I have been tring to configure a sharepoint backup on a machine with a dual
> > nic setup.  According to EMC 2 nic setups are not supported has anyone been
> > able to get the backups to run with a dual nic set on both the networker
> > server and the client machine
> >
> > +----------------------------------------------------------------------
> > |This was sent by mario.ventrone AT rci.rogers DOT com via Backup Central.
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