Hi all, 
 
We took the plunge last week ourselves - besides an initial problem
resulting in hanging processes which was immediately addressed by the
following:  
 
Exact Error Message 
The application failed to initialize properly (0xc0000142). Click on OK
to terminate the application. 


Details:

Overview:
On a NetBackup 6.0 Server, errors occur in the application event log
stating "Application Error : The application failed to initialize
properly (0xc0000142). Click on OK to terminate the application."  This
may occur for several different NetBackup processes.


Troubleshooting:
These symptoms may appear if the NetBackup server has run out of
non-interactive desktop heap space.  Adjusting the size of the
non-interactive desktop heap has been known to resolve this error.
 
Once we addressed this problem - we seem to be in the clear - and have
run successful scheduled weekly fulls, monthly fulls, restore and
duplicate jobs.  Good luck 

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