I assume you mean something like this:

Back up machine ONE, which is connected to the network and can communicate
with the TSM server.
Restore some or all of the data to machine TWO, which is not on the network.

Yes, you can do this in some circumstances.  Read the doc in the TSM server
admin guide on GENERATE BACKUPSET.  You can back up machine ONE to the TSM
server, then use GENERATE BACKUPSET to put the "active" data on a portable
tape or CD.  Then you can take that tape or CD and restore it on machine
TWO, without any connection to the network.  See the client documentation on
RESTORE BACKUPSET.

You have to do some work to get compatible media, and I don't think it is
supported for all client types.