This is from the readme from the 4.2.1 client:

Novell NetWare Specific Known Problems
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    Novell NetWare Incident (Novell Internal):
    Novell NetWare Incident (Novell Internal):

         Operating System(s) affected:

              NetWare 5.1 with SP3

         Description:

              With SP3 for NetWare 5.1, Novell has made changes to CLIB
              dated 6/6/2001.

              This version of CLIB can cause the following errors:
                 (TSA500.NLM 5.4.269) No data sets can be found.

              This error is also known as SMS error FFFDFFF2 or
              File not found.  TSM will translate the error to:
                  ANS1228E Sending of Object 'FileName' failed

              This error occurs when one thread logs out of the TSA,
              it can result in other connections to the TSA of the
              same thread group being logged out.

         Circumvention:

              Work around is to regress the CLIB.NLM to previous version.
              Please contact Novell for additional information and latest
fix.